Dietary supplement

ActiFolin® 1 mg
A unique, comprehensive source of folates for individuals with an increased demand for folates

60 tablets
What is ActiFolin®?
ActiFolin® 1 mg is a groundbreaking formula containing a comprehensive source of folates:
- folic acid
- ready-to-use, better-absorbed active form of folic acid from the latest fourth generation*, designed specifically for those who may have difficulty absorbing conventional forms of folic acid. This folate is characterised by better solubility and higher bioavailability compared to third generation folate**.


Who is Actifolin® 1 mg for?
ActiFolin® 1 mg is a dietary supplement that, due to its unique comprehensive source of folates, is particularly recommended for:
- women during the menopause
- women of childbearing age planning to conceive and during pregnancy
- all women and men with an increased folate demand.
One tablet provides 0.5 mg of folic acid and 0.5 mg of the active form of folate, which is generally recognized as safe (GRAS) by the FDA (Food and Drug Administration) and has a positive opinion from EFSA (European Food Safety Authority).
Why choose ActiFolin®?
Folic acid, a common source of folate in commercially available products, must be converted by the body to its active form in order to be fully utilised by the body.
Scientific studies have shown that some individuals may have difficulty absorbing folic acid, a fact that most of us are unaware of. Research conducted on the Polish population confirmed that this issue may affect as many as 50% of individuals.1
ActiFolin® is a solution to this problem, as it contains not only traditional folic acid but also an additional source of folates in an active form that does not require further conversion by the body.

Ingredients
Fillers: cellulose, sorbitol; anti-caking agent: polyvinylpyrrolidone; thickening agent: hydroxypropyl methylcellulose; anti-caking agent: polyethylene glycol; starch; glucosamine salt of (6S)-5-methyltetrahydrofolate; pteroylmonoglutamic acid; thickening agent: hydroxypropyl cellulose; anti-caking agent: calcium sulfate; medium-chain triglycerides; colouring agent: iron oxides and hydroxides.
Active ingredients in the recommended daily dose – 1 tablet: | |
Folic acid: |
1000 µg (1 mg)
[500% GDA*] |
active form of folate (glucosamine salt of (6S)-5-methyltetrahydrofolate) |
500 µg (0,5 mg)
[250% RWS*]
|
folic acid (pteroylmonoglutamic acid) |
500 µg (0,5 mg)
[250% RWS*]
|
*RWS – % of daily reference intake values (for adults)
Directions for use
Recommended daily dose: 1 tablet. Swallow the tablet whole and wash it down with water.
Do not exceed the recommended daily dose.
Pregnant women should consult a physician before use.
Do not use if you are hypersensitive to any ingredient in the product.
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*EFSA Journal 2013;11(10):3358
** The justification for the conventional, commonly used division of chemical forms of folic acid is the chronological order of positive evaluations issued by the European Food Safety Authority (EFSA): first for calcium L-methylfolate in 2004 (EFSA Journal (2004) 135, 1-20) and then for the glucosamine salt of (6S)-5-methyltetrahydrofolate in 2013 (EFSA Journal 2013; 11(10):3358) as novel food ingredients for use in dietary supplements.
1. Seremak-Mrozikiewicz A. et al. Archives of Perinatal Medicine 19(1), 12-18, 2013.