Dietary supplement

ActiFolin®0,8 mg
Unique comprehensive source of folates for women of childbearing age planning to conceive and during pregnancy
30 tablets
90 tablets
What is ActiFolin®?
ActiFolin® 0.8 mg is a groundbreaking dietary supplement containing a comprehensive source of folates:
- folic acid,
- ready-to-use, better-absorbed active form of folic acid from the latest fourth generation**, designed specifically for those who may have difficulty absorbing conventional forms of folic acid. This folate is characterised by better solubility and higher bioavailability compared to third generation folate***.


Who is ActiFolin® 0.8 mg for?
ActiFolin® 0.8 mg is intended for:
- Women of childbearing age planning to conceive and during pregnancy.
One tablet provides 0.4 mg of folic acid and 0.4 mg of the active form of folate, which is generally recognized as safe (GRAS) by the FDA (Food and Drug Administration).
Why choose ActiFolin®?
According to expert recommendations, every future mother, as well as all women of childbearing age who may potentially become pregnant, should additionally take an adequate amount of folates — in the form of 0.4 mg of folic acid per day1-2. Unfortunately, it may happen that a woman planning to conceive or who is pregnant is unable to absorb the appropriate amount of conventional forms of folic acid. Research conducted in Poland has confirmed that this issue has a genetic basis and may affect up to 50% of women3.
ActiFolin® can be a solution to this problem, as it contains not only traditional folic acid but also an additional source of folates in an active form that does not require further conversion by the body.

Ingredients
Fillers: cellulose, sorbitol; anti-caking agent: polyvinylpyrrolidone; thickening agent: hydroxypropyl methylcellulose; anti-caking agent: polyethylene glycol; starch; glucosamine salt of (6S)-5-methyltetrahydrofolate; pteroylmonoglutamic acid; thickening agent: hydroxypropyl cellulose; anti-caking agent: calcium sulfate; medium-chain triglycerides; colouring agent: iron oxides and hydroxides. The product may contain lactose (from milk).
Active ingredients in the recommended daily dose – 1 tablet: | |
Folic acid: | 800 µg (0,8 mg) [400% RWS*; 100% RDS**] |
active form of folate (glucosamine salt of (6S)-5-methyltetrahydrofolate) | 400 µg (0,4 mg) [200% RWS*; 100% RDS**] |
Folic acid (pteroylmonoglutamic acid) | 400 µg (0,4 mg) [200% RWS*; 100% RDS**] |
*GDA – % of Guideline Daily Amount (for adults)
**RDS – RDA – Recommended Dietary Allowances as specified by experts Dębski R., Paszkowski T., Wielgoś M. Stosowanie złożonych źródeł folianów w profilaktyce wad cewy nerwowej. Standardy Medyczne/ Profilaktyka zdrowotna Nr 1. Tom 1. 2015
Directions for use
Recommended daily dose: 1 tablet. Swallow the tablet whole and wash it down with water.
Do not exceed the recommended daily dose.
Pregnant women should consult a physician before use.
Do not use if you are hypersensitive to any ingredient in the product.
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*Comprehensive source of folates
**EFSA Journal 2013;11(10):3358
*** The justification for the conventional, commonly used division of chemical forms of folic acid is the chronological order of positive evaluations issued by the European Food Safety Authority (EFSA): first for calcium L-methylfolate in 2004 (EFSA Journal (2004) 135, 1-20) and then for the glucosamine salt of (6S)-5-methyltetrahydrofolate in 2013 (EFSA Journal 2013; 11(10):3358) as novel food ingredients for use in dietary supplements.
1. Rekomendacje Polskiego Towarzystwa Ginekologicznego w zakresie stosowania witamin i mikroelementów u kobiet planujących ciążę, ciężarnych i karmiących. Ginekol.Pol. 2014, 85, 395-399.
2. Stanowisko Zespołu Ekspertów Ministerstwa Zdrowia i Opieki Społecznej. Żyw Człow Metabol 1997;24:91–95.
3. Seremak Mrozikiewicz A. i wsp. Archives of Perinatal Medicine 19(1), 12-18, 2013